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ETD Embedded Mass Spectrometer to Allow Analysis of Changes in Proteins Structures

Apr 25, 2007

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The recently released LTQ XL linear ion trap mass spectrometer of Thermo Fisher Scientific Inc. is expected to allow scientists to analyze the alterations in structures of proteins, encompassing those essential to cancer tumor growth.
 
This new equipment features ETD (Electron Transfer Dissociation) technology - a vast technique for peptide fragmentation. ETD enables accurate identification of proteins as well as provides explicit information concerning the nature and location of changes in structure of proteins, like phosphorylation.
 
“We believe ETD performed on a linear ion trap is a major turning point for the proteomics community, enabling researchers to pinpoint, identify and fully characterize more post-transitional modificatons such as phosphorylation and glycosylation than ever before,” Greg Herrema, president of Scientific Instruments for Thermo Fisher Scientific said in a statement that Laboratory Network.com published on March 9, 2007.
 
The ion trap technology may also be used for studying “how distinctive cells & their proteins interact with each other in order to pass signals”. This is a vital process joined with drug resistance, structural changes while proteins truss together, and genes’ or other molecules’ deactivation, for instance, siRNA (small interfering RNA). This approach may also be used in any of the cell system that can be labeled by SILAC (Stable Isotope Labeling With Amino Acids) in cell culture.
 
RNCOS report on “Bioinformatics Market Update (2006)” notifies, “Proteomics refers to the broad study of proteins, specifically their functions and structures. Often viewed as “next step”, proteomics has much more complications than genomics. Proteome could be illustrated as the entirety of proteins that exist in an organism all through its life span, or, if considered at smaller scale, the entirety of proteins existing in a specific cell type under a specific type of simulation.”
 
This research report “Bioinformatics Market Update (2006)” provides extensive research and objective analysis of the Bioinformatics Industry. Key facts and issues analyzed in this report include: global outlook of Bioinformatics market, analysis of the Bioinformatics market by various segments and application areas, their revenue and growth prospects, key drivers, opportunities for growth, and threats to the industry, an update on the recent developments in the Bioinformatics industry, snapshots of the key players in the Bioinformatics industry.
 
For more information visit: http://www.rncos.com/Report/IM045.htm


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