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Promising Outlook - US Cancer Vaccine Market

Promising Outlook - US Cancer Vaccine Market

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Publish Date : Aug, 2018| No. of Pages : 150

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1. Analyst View
 
2. Research Methodology
 
3. Cancer Statistics by Demographics
    3.1 Incidences and Mortality
    3.2 Leading States by Incidences
    3.3 Leading Cancers by Incidences
          3.3.1 Male Cancer Incidences
          3.3.2 Female Cancer Incidences
          3.3.3 Children Cancer Incidences
 
4. Market Dynamics
    4.1 Drivers
          4.1.1 Rising Cancer Incidences
          4.1.2 Ability to Reduce Healthcare Expenditure
          4.1.3 Rising Awareness
          4.1.4 Patient Assistance Programs
          4.1.5 Government Initiatives
          4.1.6 Strong Pipeline
          4.1.7 Technological Advancements
    4.2 Restraints
          4.2.1 High Cost of Cancer Vaccines
          4.2.2 Side-Effects of Cancer Vaccines
          4.2.3 Vaccine Supply Shortages
          4.2.4 Insurance Issues Related to Cancer Vaccination
    4.3 Opportunities
          4.3.1 Therapeutic Cancer Vaccines
          4.3.2 Adjuvant Cancer Vaccines
 
5. Cancer Vaccines Market Outlook
    5.1 Key Product Analysis
          5.1.1 Provenge
                   5.1.1.1 Market Analysis
                   5.1.2 T-Vec/Imlygic
                            5.1.2.1 Market Analysis
                   5.1.3 HPV Vaccine
                            5.1.3.1 Gardasil
                                        5.1.3.1.1 Market Analysis
                            5.1.3.2 Cervarix
                                        5.1.3.2.1 Market Analysis
                    5.1.4 HBV Vaccines
                             5.1.4.1 Engerix-B & Twinrix
                                         5.1.4.1.1 Market Analysis
                             5.1.4.2 Recombivax HB
                                         5.1.4.2.1 Market Analysis
                             5.1.4.3 Pediarix/ Infanrix
                                         5.1.4.3.1 Market Analysis
 
6. Cancer Vaccines Market by Cancer Type
 
7. Cancer Vaccine Market by Application
 
8. Potential Cancer Vaccine Candidates: An Opportunity Assessment
    8.1 Prophylactic Vaccine
    8.2 Therapeutic Vaccine
           8.2.1 Prostate Cancer
           8.2.2 Breast Cancer
           8.2.3 Lung Cancer
           8.2.4 Colorectal Cancer
 
9. US Patent Analysis
    9.1 Patents by Year
    9.2 Patents by Category
           9.2.1 Utility Patents
           9.2.2 Design Patents
           9.2.3 Plant Patents
    9.3 Patents by Company
    9.4 Patents by Assignee Type
          9.4.1 By Assignee Name
          9.4.2 By Assignee State
 
10. Regulatory Environment
      10.1 Vaccine Approval Process
      10.2 FDA Guidance for Industry: Clinical Considerations for Therapeutic Cancer Vaccines
              10.2.1 Considerations for both Early and Late Phase Clinical Trials
                         10.2.1.1 Patient Population
                         10.2.1.2 Monitoring the Immune Response
                         10.2.1.3 Biomarkers as Evidence of Efficacy
                         10.2.1.4 Adjuvants Used to Stimulate Immune Response
                         10.2.1.5 Multi-antigen Vaccines
                         10.2.1.6 Disease Progression/Recurrence Immediately or Shortly after the Initial Administration of Cancer Vaccines
                         10.2.1.7 Concomitant and Subsequent Therapies
              10.2.2 Considerations for Early Phase Clinical Trials
                         10.2.2.1 Starting Dose and Dosing Schedule
                         10.2.2.2 Booster and Maintenance Therapy
                         10.2.2.3 Dose Escalation
                         10.2.2.4 Single-arm versus Randomized Phase-2 Trials in Early Development
               10.2.3 Considerations for Late Phase Clinical Trials
                          10.2.3.1 Safety Profile from Early Phase Clinical Trials
                          10.2.3.2 Endpoints
                          10.2.3.3 Statistical Issues
                          10.2.3.4 Control Issues
                          10.2.3.5 Delayed Vaccine Effect
                          10.2.3.6 Autologous Vaccine Trials
                          10.2.3.7 Accelerated Approval Regulations
 
11. Competitive Landscape
 
12. Company Profiles
      12.1 Merck & Co., Inc.
      12.2 GlaxoSmithKline plc.
      12.3 Dendreon Pharmaceuticals LLC
      12.4 Amgen Inc.
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